By Dennis Thompson HealthDay Reporter
FRIDAY, March 29, 2024 — Individuals taking weight-loss medicine like Ozempic and Wegovy have to drop them within the days or even weeks previous to surgical procedure, a brand new research warns.
Of us on one in every of these medicine — often known as GLP-1 receptor agonists — have a 33% larger danger of creating pneumonia by inhaling their very own vomit throughout surgical procedure, researchers discovered.
“Aspiration throughout or after endoscopy could be devastating,” stated researcher Dr. Ali Rezaie, medical director of the GI Motility Program at Cedars-Sinai Medical Middle in Los Angeles.
“If important, it will possibly result in respiratory failure, ICU admission and even demise,” Rezaie stated. “Even delicate instances might require shut monitoring, respiratory assist and medicines together with antibiotics. It is crucial we take all attainable precautions to forestall aspiration from occurring.”
Individuals are sometimes requested to quick previous to surgical procedure as a result of common anesthesia may cause nausea, they usually may inhale and choke on their very own vomit.
Sadly, a part of the way in which that GLP-1 receptor agonists assist immediate weight reduction is by slowing the digestion course of, researchers stated. Meaning it takes longer for meals to move by way of the abdomen.
These outcomes jibe with steerage issued final 12 months by the American Society of Anesthesiologists that requires screening for weight-loss drug use earlier than surgical procedure, and informing sufferers of the dangers concerned.
Additional, one other research revealed earlier this month within the journal JAMA Surgical procedure discovered that about 56% of individuals taking these medicine nonetheless have important quantities of meals of their abdomen on the time of surgical procedure.
For this newest research, researchers analyzed the information from practically 1 million U.S. sufferers who underwent an endoscopy between January 2018 and December 2020. Endoscopies contain lengthy versatile tubes inserted into the mouth or anus, by way of which medical doctors can look at the GI tract for indicators of sickness.
They discovered that individuals on the weight-loss medicine had a 33% higher danger of aspiration pneumonia.
The brand new research was revealed March 27 within the journal Gastroenterology.
“Once we apply this danger to the greater than 20 million endoscopies which are carried out within the U.S. annually, there may very well be numerous instances the place aspiration might be prevented if the affected person safely stops their GLP-1RA treatment prematurely,” Rezaie stated in a Cedars Sinai information launch.
“The outcomes of this research may change medical observe,” stated lead researcher Dr. Yee Hui Yeo, a medical fellow within the Karsh Division of Gastroenterology and Hepatology at Cedars-Sinai. “Sufferers taking these medicines who’re scheduled to bear a process ought to talk with their healthcare workforce properly prematurely to keep away from pointless and undesirable issues.”
Sources
- Cedars-Sinai Medical Middle, information launch, March 27, 2024
Disclaimer: Statistical information in medical articles present common tendencies and don’t pertain to people. Particular person components can differ drastically. At all times search customized medical recommendation for particular person healthcare selections.
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Posted March 2024
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