SINGAPORE – MR elastography is a number one noninvasive method for imaging liver fibrosis, but a brand new method referred to as “3D MRE” guarantees to open new alternatives for diagnosing continual liver illness, in response to a main knowledgeable within the discipline.
Sudhakar Venkatesh, MD, gave a chat on the method on Could 4 on the Worldwide Society for Magnetic Resonance in Drugs (ISMRM) 2024 assembly. In an interview with AuntMinnie.com, he mentioned 3D MRE is promising for differentiating irritation from fibrosis and bettering diagnostic accuracy for liver fibrosis staging.
“3D MRE can also acquire the elastography info of almost your entire or a giant a part of the liver versus 2D elastography, which solely take about three or 4 slices,” he mentioned.
What’s the distinction between 2D and 3D MR elastography?
In essence, 3D MRE offers a number of new mechanical parameters, together with what are referred to as storage modulus, loss modulus, wave attenuation, damping ratio, and volumetric pressure. Together with two or extra of these parameters are promising for differentiating irritation from fibrosis, a discovering tough to attain with a 2D method, Venkatesh famous.
3D MRE offers a chance for analysis of latest mechanical parameters.
Venkatesh famous that on the Mayo Clinic in Rochester, he and colleagues are concerned in research utilizing 3D MRE to evaluate whether or not new medication are efficient for liver illness, together with metabolic-dysfunction-associated steatotic liver illness, or MASLD (beforehand referred to as non-alcoholic fatty liver illness (NAFLD), the commonest liver illness within the U.S. and the world.
What the long run instructions for the know-how?
In the end, these advances are paving the best way for a future the place multiparametric-MRI turns into the gold commonplace for evaluating liver fibrosis, providing a safer, extra correct, and fewer invasive method for sufferers and clinicians alike, Venkatesh mentioned.
