Excessive-Throughput Platform Reduces Guide Steps by as much as 90%.
Picture Credit score: Beckman Coulter Life Sciences
Beckman Coulter Life Sciences, a world chief in laboratory automation and innovation, and an organization of Danaher Company (NYSE: DHR), launches the Cydem VT Automated Clone Screening System, a revolutionary high-throughput microbioreactor platform for automated prime clone screening.
The brand new Cydem VT System considerably reduces time to marketplace for biologic drug discovery and monoclonal antibody-based therapeutics, by slashing guide laboratory steps in Cell Line Improvement as much as 90% in a single experiment, and eliminating the necessity for a lot of subsequent conventional screening steps.
By delivering early solutions for cell progress and productiveness within the cell line improvement course of, the Cydem VT System gives labs with extra dependable clones in comparison with conventional strategies, together with higher cultivation circumstances which might be nearer to biomanufacturing manufacturing. The all-in-one high-throughput screening platform is good in cell line improvement of Chinese language Hamster Ovary (CHO) cell traces producing monoclonal antibodies (mAbs).
“Our Cydem VT Automated Clone Screening System affords an thrilling revolution to expedite vital analysis therapies for diseases, together with autoimmune illnesses and lots of sorts of most cancers,” mentioned Product Supervisor Dr. Sebastian Hofzumahaus. “We heard the considerations about deciding on poor productiveness clones and understood the vital must develop an easy-to-use answer that confidently and persistently identifies the very best clones. By way of offering early solutions and higher cultivation circumstances, we’re in a position to make sure larger accuracy with fewer steps to scale back the danger of unhealthy clones to assist laboratories uncover their subsequent massive breakthrough even sooner and positively influence human well being.”
The system combines a number of trusted Beckman Coulter Life Sciences applied sciences together with microbioreactor, liquid dealing with, antibody titer and cell well being (cell rely & viability) measurements into one superior platform that empowers lab managers with a simpler, higher-throughput technique for prime clone screening. It permits parallel pH-controlled, fed-batch cultivation and monitoring of as much as 96 bioreactors with particular person gassing.
Automated operations present not less than three days of walk-away time throughout an experiment. On-line, non-invasive pH, dissolved oxygen (DO) and biomass measurements present steady management over vital cultivation parameters. On-deck dedication of cell focus, viability and titer focus guarantee knowledgeable collection of the highest clones. Be taught extra concerning the Cydem VT Automated Clone Screening System by clicking right here.
About Beckman Coulter Life Sciences
With a relentless mission to empower these in search of solutions to life’s essential scientific questions, Beckman Coulter Life Sciences is a most well-liked laboratory companion offering automation and innovation options for Centrifugation, Stream Cytometry, Genomics, Particle Evaluation, and Liquid Dealing with workflows. With a legacy courting again to 1935, our applied sciences scale back guide laboratory processes and may present larger velocity, accuracy, and superior analytics to speed up solutions with a guiding focus to enhance affected person care and allow pioneering discoveries. Beckman Coulter Life Sciences, a part of the Danaher Company (NYSE: DHR) household of worldwide science and know-how corporations, is headquartered in Indianapolis, Indiana with 11 operational hubs world wide and employs roughly 2,800 associates with greater than 400,000 methods put in globally. Get to know us by clicking right here and by following us on LinkedIn.
Product not to be used in diagnostic or therapeutic procedures. Product in improvement. Efficiency traits haven’t been validated.
