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Monday, January 27, 2025

Swiss group produces first 3D PET/MRI picture


Researchers on the College of Zurich in Switzerland say they’ve produced the primary cinematically rendered picture from a affected person based mostly on an ordinary medical F-18 FDG-PET/MRI scan.

The 3D picture is from a affected person with an oropharyngeal carcinoma within the right-sided taste bud and palatine tonsil, famous first creator and nuclear drugs doctor Martin W. Huellner, MD, and colleagues.

“Traditionally, [cinematic rendering] has primarily centered on CT pictures, with sporadic situations famous in PET/CT; nevertheless, its use in PET/MR stays unreported thus far,” the group wrote. The article was revealed on July 1 within the European Journal of Nuclear Drugs and Molecular Imaging and featured because the journal’s Picture of the Month.

Signa PET/MR scanner (GE HealthCare, Waukesha, WI) MR image: T1-weighted LAVA-flex, repetition time, 4.65 ms; echo time, 1.82 ms; flip angle, 15°; slice thickness,1.3 mm; spacing, 2.6 mm; field of view; 100 mm; total acquisition time; 1:31 minutes. PET image: 245 MBq of F-18 FDG, bed time, 1:30 minutes; reconstructed using block-sequential regularized expectation maximization. Image courtesy of Huellner et al. Licensed under CC BY 4.0.Signa PET/MR scanner (GE HealthCare, Waukesha, WI) MR picture: T1-weighted LAVA-flex, repetition time, 4.65 ms; echo time, 1.82 ms; flip angle, 15°; slice thickness,1.3 mm; spacing, 2.6 mm; area of view; 100 mm; whole acquisition time; 1:31 minutes. PET picture: 245 MBq of F-18 FDG, mattress time, 1:half-hour; reconstructed utilizing block-sequential regularized expectation maximization. Picture courtesy of Huellner et al. Licensed underneath CC BY 4.0.Picture courtesy of the European Journal of Nuclear Drugs and Molecular Imaging.

Developed as a fusion of radiology and cinematography, cinematic rendering transcends conventional rendering strategies and gives lifelike representations that bridge the hole between medical pictures and actuality, the authors wrote. It’s a postprocessing method based mostly on the segmentation of commonplace pictures into photorealistic 3D representations, facilitating spatial orientation.

The picture was retrospectively reconstructed from a commonplace F-18 FDG-PET/MRI medical picture dataset acquired from the affected person inside lower than two minutes of scan time utilizing the software program Cinematic Anatomy (Siemens Healthineers, Erlangen, Germany), they famous.

“Such photorealistic pictures may probably assist radiologists in reporting and surgeons in preoperative planning by providing essential anatomical landmarks, enhancing visualization of subsurface constructions, and complementing endoscopic pictures,” the group concluded.

Huellner’s co-authors included Grégoire Morand, MD, of the division of otolaryngology-head and neck surgical procedure; Bernd Stadlinger, MD, of the Clinic of Cranio-Maxillofacial and Oral Surgical procedure; and Klaus Engel, PhD, of Siemens Healthineers.

The complete article is accessible right here.

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